Ted Talk: Wat dokters niet weten over de geneesmiddelen die ze voorschrijven

Als een nieuw geneesmiddel wordt getest, zouden de resultaten voor de rest van de medische wereld moeten worden gepubliceerd. Maar vaak worden negatieve of voorlopige resultaten niet gepubliceerd waardoor dokters in het ongewisse blijven. In deze gepassioneerde talk legt Ben Goldacre uit waarom deze ongepubliceerde negatieve data zo buitengewoon misleidend en gevaarlijk zijn. Nederlands transcript

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A Randomized Trial of Combined Citalopram and Naltrexone for Nonabstinent Outpatients With Co-Occurring Alcohol Dependence and Major Depression

Despite the high rate of co-occurrence of major depression and alcohol dependence, the role of pharmacotherapy in their treatment remains unclear. In the new era of naltrexone for alcohol dependence, it is notable that only 1 study to date has examined the efficacy of antidepressant medication prescribed concurrently with naltrexone. We aimed to determine whether […]

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Clozapine revisited: Impact of clozapine vs olanzapine on health care use by schizophrenia patients on Medicaid

Our purpose was to evaluate health care use and cost patterns for clozapine compared with olanzapine in the treatment of schizophrenia. METHODS: Health care outcomes were measured over a 1-year post-treatment period for episodes of antipsychotic therapy initiated between 1997 and 2002. Four episode categories were defined: restart after lapse in therapy, switch after break, […]

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